Friday, 17 April 2015

High-throughput SNP genotyping at IRRI

An IRRI Seminar

By Michael J. Thomson
Senior Scientist-Molecular Genetics and Marker Applications
Plant Breeding, Genetics, and Biotechnology

23 April  2015
1:15-2:15 p.m.
Havener Auditorium


Every so often, there come advances so far-reaching that they transform our approaches to doing science. Recently, we have experienced the convergence of three revolutions in the biological sciences: next-generation sequencing, information technology, and high-throughput genotyping techniques. Combined, these technologies present a tremendous opportunity for accelerating progress in genetic discovery and applications in plant breeding. By using automated single nucleotide polymorphism (SNP) systems, rapid and precise molecular marker genotyping is now routine.

In his exit seminar, Dr. Thomson will describe the efforts of the service and research teams in the Genotyping Services Laboratory to implement high-throughput SNP genotyping at IRRI and leverage the latest tools and data sets to validate predictive SNP markers for the breeding programs. While SNP genotyping has successfully accelerated discovery research at IRRI, more work is needed to deploy low-cost SNP markers on a large scale across the forward breeding programs. Dr. Thomson will also discuss recent initiatives to integrate SNP analysis pipelines, databases, and breeding data management tools to enable rapid analysis of industrial-scale genotyping across IRRI’s breeding programs for more effective marker-assisted selection.

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