An IRRI Seminar
By Gisela P. Concepcion
Vice President for Academic Affairs
University of the Philippines System
The Marine Science Institute
University of the Philippines Diliman
26 March 2015
Marine bacteria have been a rich source of novel bioactive compounds for many years. In many cases, these bacteria have been found in close association with marine invertebrates. In our research program, bacteria are isolated from dissected tissues of marine mollusks and cultured in the laboratory. Small-scale cultures undergo preliminary bioactivity screening and are prioritized for isolation and purification of bioactive compounds. In this talk, we will present our work on some of the bacterial isolates and the compounds they produce, which exhibit significant neuroactivity and antimicrobial activity. These compounds are being pursued further as potential drugs. Work on microbial genomes showing the biosynthesis genes and pathways for these compounds will also be presented.